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Search Results for " hepatitis b virus "

20

Compounds

Cat No. Product Name Synonyms Targets
TP2231 HBcAg [Hepatitis B virus] (18-27) Others
HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person.
TP1520 Hepatitis B Virus Core (128-140) Hepatitis B Virus Core 128-140
The hepatitis B virus (HBV) core protein has been found in the nucleus, the cytoplasm, or both of HBV-infected hepatocytes. nuclear localization of the HBV core protein is negatively regulated by phosphorylation during t...
T4S1718 Punicalin HBV , HIV Protease
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM).
T23407 Surface antigen (208-215) [Hepatitis B Virus] Others
The nucleocapsid of the hepatitis B virus is covered by an envelope of HBV surface antigen (HBsAg), which has the common, group-specific determinant a. The four major subtypes of HBsAg, adw, adr, ayw and ayr, are generat...
TN1482 Chamaechromone P450 , HBV
Chamaechromone is a natural product isolated from the roots of Stellera chamaejasme L.. Chamaechromone has anti-HBV and insecticidal activity.
T11669 IR415 HBV
IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx protein on the activity of the dicer endoribonuclease. IR415 i...
T27527 HBF-0259 HBF 0259 Antiviral
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV...
T3S0872 Paederoside Antiviral , HBV
1. Paederoside is a potent deterrent against the beetle was isolated from the aphid . 2. Paederoside displays high anti-tumor promoting activity against the Epstein-Barr virus activation.
T16366 NVR 3-778 HBV
NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM belonging to the SBA class It has anti-HBV activity.
T5832 Besifovir HBV
Besifovir, a parent drug converted by LB80380, further metabolizes to its active form, LB80317. LB80380 is potent antiviral agent against hepatitis B virus (HBV).
T2780 Catalpol Catalpinoside,Digitalis purpurea L Others , HBV
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.
T3273 Bifendate Bifendatatum HBV , Reverse Transcriptase
Bifendate (Bifendatatum) is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.
T20048 Vidarabine phosphate Antiviral
Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties.
T4475 JNJ-632 HBV
JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator.
TQ0248 Alisol F HBV
Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities.
T11409 GLP-26 HBV
GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM...
T6846 Vesatolimod GS-9620 Apoptosis , HCV Protease , HBV , TLR , HIV Protease
Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.
TQ0017 AB-423 HBV
AB-423 is an inhibitor of HBV capsid assembly, and potently inhibits HBV replication (EC50/EC90: 0.08-0.27 μM/0.33-1.32 μM in cells).
T1922 Pseudolaric Acid B Apoptosis , p38 MAPK , Ferroptosis , HBV , Autophagy , Antifungal
Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.
T15573 Inarigivir soproxil SB9200 HCV Protease
Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype ...
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